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Therapeutic doses of colchicine should be reserved for patients in whom these other agents are contraindicated or ineffective {05}. Colchicine may provide additional benefit when used concurrently with ursodiol for this indication {30}. Colchicine has no analgesic {01} {02} {03} {06} or antihyperuricemic {01} {02} {03} {04} {06} activity. Colchicine has permitted withdrawal of corticosteroid therapy in some patients with this condition {36} {37} {38}. Ask your health care provider if Colchicine/Probenecid may interact with other medicines that you take. Colchicine has been used together with melphalan and prednisone for the treatment of primary amyloidosis {17} {18}.
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